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1.

Distinct metabolic programs established in the thymus control effector functions of Î³Î´ T cell subsets in tumor microenvironments.

Lopes, Noella; McIntyre, Claire; Martin, Stefania; Raverdeau, Mathilde; Sumaria, Nital; Kohlgruber, Ayano C; Fiala, Gina J; Agudelo, Leandro Z; Dyck, Lydia; Kane, Harry; Douglas, Aaron; Cunningham, Stephen; Prendeville, Hannah; Loftus, Roisin; Carmody, Colleen; Pierre, Philippe; Kellis, Manolis; Brenner, Michael; Argüello, Rafael J; Silva-Santos, Bruno; Pennington, Daniel J; Lynch, Lydia.

Nat Immunol; 22(2): 179-192, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33462452

2.

Author Correction: Î³Î´ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

Kohlgruber, Ayano C; Gal-Oz, Shani T; LaMarche, Nelson M; Shimazaki, Moto; Duquette, Danielle; Koay, Hui-Fern; Nguyen, Hung N; Mina, Amir I; Paras, Tyler; Tavakkoli, Ali; von Andrian, Ulrich; Uldrich, Adam P; Godfrey, Dale I; Banks, Alexander S; Shay, Tal; Brenner, Michael B; Lynch, Lydia.

Nat Immunol; 20(3): 373, 2019 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-30728493

3.

Î³Î´ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

Kohlgruber, Ayano C; Gal-Oz, Shani T; LaMarche, Nelson M; Shimazaki, Moto; Duquette, Danielle; Koay, Hui-Fern; Nguyen, Hung N; Mina, Amir I; Paras, Tyler; Tavakkoli, Ali; von Andrian, Ulrich; Uldrich, Adam P; Godfrey, Dale I; Banks, Alexander S; Shay, Tal; Brenner, Michael B; Lynch, Lydia.

Nat Immunol; 19(5): 464-474, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29670241

4.

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.

Michelet, Xavier; Dyck, Lydia; Hogan, Andrew; Loftus, Roisin M; Duquette, Danielle; Wei, Kevin; Beyaz, Semir; Tavakkoli, Ali; Foley, Cathriona; Donnelly, Raymond; O'Farrelly, Cliona; Raverdeau, Mathilde; Vernon, Ashley; Pettee, William; O'Shea, Donal; Nikolajczyk, Barbara S; Mills, Kingston H G; Brenner, Michael B; Finlay, David; Lynch, Lydia.

Nat Immunol; 19(12): 1330-1340, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30420624

5.

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

Assmann, Nadine; O'Brien, Katie L; Donnelly, Raymond P; Dyck, Lydia; Zaiatz-Bittencourt, Vanessa; Loftus, Róisín M; Heinrich, Paul; Oefner, Peter J; Lynch, Lydia; Gardiner, Clair M; Dettmer, Katja; Finlay, David K.

Nat Immunol; 18(11): 1197-1206, 2017 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-28920951

6.

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue.

Lynch, Lydia; Michelet, Xavier; Zhang, Sai; Brennan, Patrick J; Moseman, Ashley; Lester, Chantel; Besra, Gurdyal; Vomhof-Dekrey, Emilie E; Tighe, Mike; Koay, Hui-Fern; Godfrey, Dale I; Leadbetter, Elizabeth A; Sant'Angelo, Derek B; von Andrian, Ulrich; Brenner, Michael B.

Nat Immunol; 16(1): 85-95, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25436972

7.

New Job for NK Cells: Architects of the Tumor Microenvironment.

Dyck, Lydia; Lynch, Lydia.

Immunity; 48(1): 9-11, 2018 01 16.

Artículo en Inglés | MEDLINE | ID: mdl-29343443

8.

Î³Î´ T cells unveil invisible tumors.

Koay, Hui-Fern; Lynch, Lydia.

Trends Immunol; 44(3): 159-161, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36754745

9.

Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity.

Boulenouar, Selma; Michelet, Xavier; Duquette, Danielle; Alvarez, David; Hogan, Andrew E; Dold, Christina; O'Connor, Donal; Stutte, Suzanne; Tavakkoli, Ali; Winters, Desmond; Exley, Mark A; O'Shea, Donal; Brenner, Michael B; von Andrian, Ulrich; Lynch, Lydia.

Immunity; 46(2): 273-286, 2017 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-28228283

10.

Human Granzyme K Is a Feature of Innate T Cells in Blood, Tissues, and Tumors, Responding to Cytokines Rather than TCR Stimulation.

Duquette, Danielle; Harmon, Cathal; Zaborowski, Alexandra; Michelet, Xavier; O'Farrelly, Cliona; Winter, Des; Koay, Hui-Fern; Lynch, Lydia.

J Immunol; 211(4): 633-647, 2023 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-37449888

11.

High-Fat Diet Rapidly Modifies Trafficking, Phenotype, and Function of Plasmacytoid Dendritic Cells in Adipose Tissue.

Stutte, Susanne; Ishikawa-Ankerhold, Hellen; Lynch, Lydia; Eickhoff, Sarah; Nasiscionyte, Simona; Guo, Chenglong; van den Heuvel, Dominic; Setzensack, Daniel; Colonna, Marco; Maier-Begandt, Daniela; Weckbach, Ludwig; Brocker, Thomas; Schulz, Christian; Walzog, Barbara; von Andrian, Ulrich.

J Immunol; 208(6): 1445-1455, 2022 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-35181637

12.

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.

Wu, Di; Hu, Di; Chen, Hao; Shi, Guoming; Fetahu, Irfete S; Wu, Feizhen; Rabidou, Kimberlie; Fang, Rui; Tan, Li; Xu, Shuyun; Liu, Hang; Argueta, Christian; Zhang, Lei; Mao, Fei; Yan, Guoquan; Chen, Jiajia; Dong, Zhaoru; Lv, Ruitu; Xu, Yufei; Wang, Mei; Ye, Yong; Zhang, Shike; Duquette, Danielle; Geng, Songmei; Yin, Clark; Lian, Christine Guo; Murphy, George F; Adler, Gail K; Garg, Rajesh; Lynch, Lydia; Yang, Pengyuan; Li, Yiming; Lan, Fei; Fan, Jia; Shi, Yang; Shi, Yujiang Geno.

Nature; 559(7715): 637-641, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-30022161

13.

Unveiling the epigenomic mechanisms of acquired platinum-resistance in high-grade serous ovarian cancer.

Silva, Romina; Glennon, Kate; Metoudi, Michael; Moran, Bruce; Salta, Sofia; Slattery, Karen; Treacy, Ann; Martin, Terri; Shaw, Jacqui; Doran, Peter; Lynch, Lydia; Jeronimo, Carmen; Perry, Antoinette S; Brennan, Donal J.

Int J Cancer; 153(1): 120-132, 2023 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-36883413

14.

Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1.

Clancy-Thompson, Eleanor; Chen, Gui Zhen; LaMarche, Nelson M; Ali, Lestat R; Jeong, Hee-Jin; Crowley, Stephanie J; Boelaars, Kelly; Brenner, Michael B; Lynch, Lydia; Dougan, Stephanie K.

EMBO J; 38(14): e101260, 2019 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-31304630

15.

Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model.

Varghese, Bindu; Lynch, Lydia; Vriend, Lianne E; Draganov, Dobrin; Clark, Justice M; Kissick, Haydn T; Varghese, Sharlin; Sanda, Martin G; Dranoff, Glenn; Arredouani, M Simo; Balk, Steven P; Exley, Mark A.

Cancer Immunol Immunother; 71(12): 2943-2955, 2022 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-35523889

16.

Innate Immune Control of Adipose Tissue Homeostasis.

Kane, Harry; Lynch, Lydia.

Trends Immunol; 40(9): 857-872, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31399336

17.

The therapeutic and prognostic implications of immunobiology in colorectal cancer: a review.

Zaborowski, Alexandra M; Winter, Des C; Lynch, Lydia.

Br J Cancer; 125(10): 1341-1349, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34302062

18.

Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.

Lynch, Lydia; Nowak, Michael; Varghese, Bindu; Clark, Justice; Hogan, Andrew E; Toxavidis, Vasillis; Balk, Steven P; O'Shea, Donal; O'Farrelly, Cliona; Exley, Mark A.

Immunity; 37(3): 574-87, 2012 Sep 21.

Artículo en Inglés | MEDLINE | ID: mdl-22981538

19.

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.

O'Brien, Aisling; Loftus, Roisin M; Pisarska, Marta M; Tobin, Laura M; Bergin, Ronan; Wood, Nicole A W; Foley, Cathriona; Mat, Arimin; Tinley, Frances C; Bannan, Ciaran; Sommerville, Gary; Veerapen, Natacha; Besra, Gurdyal S; Sinclair, Linda V; Moynagh, Paul N; Lynch, Lydia; Finlay, David K; O'Shea, Donal; Hogan, Andrew E.

J Immunol; 202(12): 3404-3411, 2019 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-31076528

20.

Adipose tissue at the nexus of systemic and cellular immunometabolism.

Kohlgruber, Ayano C; LaMarche, Nelson M; Lynch, Lydia.

Semin Immunol; 28(5): 431-440, 2016 10.

Artículo en Inglés | MEDLINE | ID: mdl-27789087

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